Reactivity of the ventromedial prefrontal cortex, but not the amygdala, to negative emotion faces predicts greed personality trait

Table 3 Brain regions of task-based and resting-state FCs in vmPFC and GPT

Measure	Brian region	Cluster size (voxels)	MNI Coordinates			Z
Measure	Brian region	Cluster size (voxels)	x	y	z	Z
vmPFC-based PPI High < Low group on the contrast of A > N (Cohort 1)	L Superior Frontal Gyrus	128	− 18	28	62	4.27
	L Middle Frontal Gyrus	71	− 36	8	64	4.19
	R Middle Frontal Gyrus	66	28	10	32	3.99
	L Middle Temporal Gyrus	55	− 66	− 22	− 16	3.64
	L Orbitofrontal Cortex	51	− 30	34	− 2	4.18
	L Lateral Occipital Cortex	47	− 52	− 60	40	3.68
	R Thalamus	45	12	− 8	18	4.03
	L Thalamus	43	− 8	− 8	14	4.11
	L Frontal Pole	37	− 36	46	− 6	3.71
vmPFC-based PPI High < Low group on the contrast of F > N (Cohort 1)	L Superior Frontal Gyrus	80	− 18	28	62	4.07
	R Middle Frontal Gyrus	75	28	16	30	4.20
	L Orbitofrontal Cortex	49	− 30	34	− 2	3.93
	L Middle Frontal Gyrus	35	− 44	16	36	3.79
	L Middle Temporal Gyrus	34	− 62	− 24	− 14	3.79
vmPFC-based rsFC Positive correlation (Cohort 2)	L Angular	84	− 40	− 54	52	3.61
	R Middle Temporal Gyrus	34	58	− 36	− 6	3.54
	L Superior Parietal Lobule	28	− 26	− 50	44	3.43
	R Parahippocampus	28	32	− 30	− 18	4.27
	L Middle Frontal Gyrus	25	− 32	− 2	62	3.30

Task-based PPI analyses revealed weaker functional connectivity of vmPFC-seed with several brain regions on the contrast of angry > neutral faces and fearful > neutral faces in high group compared to group with low scores of GPT in Cohort 1. Resting-state functional connectivity analyses showed positive correlations between GPT and vmPFC-seed FC with several regions in Cohort 2
L Left, R Right, F Fearful face, A Angry face, N Neutral face, vmPFC ventromedial prefrontal cortex

ISSN: 1744-9081