Reactivity of the ventromedial prefrontal cortex, but not the amygdala, to negative emotion faces predicts greed personality trait

Table 2 Brain region activations responding to negative emotion faces and their links with GPT in Cohort 1

Measure	Brain region	Cluster size (voxels)	MNI coordinates			Z
Measure	Brain region	Cluster size (voxels)	x	y	z	Z
F + A > S	L Amygdala	216	− 18	− 6	− 14	8.80
	R Amygdala	269	26	− 2	− 16	8.19
	R Frontal Pole/vmPFC	392	4	54	− 14	5.09
	R Middle Frontal Gyrus	1711	52	20	30	5.71
	L Inferior Frontal Gyrus	295	− 40	14	26	4.69
	R Lateral Occipital Cortex	2046	22	− 94	− 10	12.50
	L Occipital Fusiform Gyrus	254	− 28	− 84	− 16	12.01
	R Occipital Fusiform Gyrus	268	24	− 86	− 16	11.88
	R Superior Temporal Gyrus	278	50	− 8	− 16	5.51
	L Middle Frontal Gyrus	252	− 34	− 2	48	4.84
	R Orbitofrontal Cortex	162	34	32	− 14	5.59
	L Orbitofrontal Cortex	34	− 40	26	− 14	4.06
	L Hippocampus	433	54	60	29	8.8
	R Hippocampus	550	36	62	28	8.19
	L Lingual	1177	59	19	28	12
	R Lingual	1147	34	16	31	12.5
	L Precentral gyrus	241	62	62	60	4.84
	R Precentral gyrus	528	24	67	51	5.71
	R cerebellum	154	2	− 54	-34	5.19
F + A > S & GPT )(-)	R vmPFC	104	2	50	0	4.26
	R Supramarginal Gyrus	64	68	− 38	20	3.81
	R Angular	32	44	− 46	20	4.02
	L Cerebellum	32	− 38	− 56	− 42	3.64
	R Superior Temporal Gyrus	32	62	2	− 4	3.98
A > N & GPT(-)	L vmPFC	49	− 8	34	− 10	3.72
A > N & GPT(-)	L Medial Frontal Cortex	33	− 2	44	− 20	3.55
F > N & GPT (-)	L vmPFC	104	− 4	50	− 12	3.68
	R Cingulate Cortex	38	12	− 46	30	3.51
	R Cerebellum	31	28	− 74	− 32	3.60

Significant brain regions were presented on the contrast of fearful + angry faces > shapes in Cohort 1. Brain reactivity on the contrasts of fearful + angry faces > shapes, angry > neutral faces, and fearful > neutral faces, were positively correlated with GPT in Cohort 1.
R right, L Left, vmPFC ventromedial prefrontal cortex, F Fearful face, A Angry face, N Neutral face, GPT greed personality trait, - negative correlation between GPT and brain activation

ISSN: 1744-9081