Specific brain imaging alterations underlying autistic traits in children with attention-deficit/hyperactivity disorder

Table 3 Independent variables of mALFF clusters related to SNAP-IV and ASSQ sub-scores in children with ADHD (N = 45)

Dependent variable	Independent variable	Standardized coefficient	t-value	P1	r²/r²adj	P
Inattention	Intercept	–	6.09	< 0.0001	0.1524/0.1120	0.0311
	Left MTG	− 0.2116	− 1.48	0.1456
	Sex	− 0.3083	− 2.16	0.0365
HI	Intercept	–	− 0.87	0.3907	0.1160/0.0954	0.0221
	FSIQ	0.3406	2.38	0.0221
Social interaction	Intercept	–	5.37	< 0.0001	0.2438/0.2262	0.0006
Social interaction	Right PL/precuneus	− 0.4937	− 3.72	0.0006^***
Communication problems	Intercept	–	2.86	0.0066	0.3769/0.3146	0.0007
	Right MTG	0.2415	1.92	0.0620
	Right PL/precuneus	− 0.3758	− 2.83	0.0073^**
	FSIQ	− 0.2109	− 1.57	0.1251
	Sex	− 0.3057	− 2.41	0.0209
RRBs	Intercept	–	2.14	0.0379	0.4210/0.3786	< 0.0001
	Right MTG	0.3707	3.10	0.0035^**
	Right PL/precuneus	− 0.4616	− 3.87	0.0004^***
	Sex	− 0.2360	− 1.98	0.0544

mALFF mean amplitude of low-frequency fluctuations. SNAP-IV Swanson, Nolan, and Pelham rating scale, version IV. ASSQ Autism Spectrum Screening Questionnaire. HI hyperactivity and impulsivity. RRBs restrictive and repetitive behaviors. FSIQ Full-Scale Intelligence Quotient. MTG middle temporal gyrus. PL parietal lobe. r²: determination coefficient; r²adj: adjusted determination coefficient, P: overall significance of multiple stepwise linear regression, P1: significance of standardized partial regression coefficient. ^**P < 0.01, ^***P < 0.001

ISSN: 1744-9081