Fig. 1
From: Inhibition of NLRP1 inflammasome improves autophagy dysfunction and Aβ disposition in APP/PS1 mice
Effects of aging on Aβ generation and neuronal damage in APP/PS1 mice. A The bands of APP, BACE1, NCSTN, Aβ1-42 and β-actin (Western blot); B The relative expression of APP over WT-9 M; C The relative expression of BACE1 over WT-9 M; D The relative expression of NCSTN over WT-9 M; E The relative expression of Aβ1-42 over WT-9 M. F The relative mRNA expression of APP over WT-9 M (q-PCR); G The relative mRNA expression of BACE1 over WT-9 M (q-PCR); H The relative mRNA expression of NCSTN over WT-9 M (q-PCR). I The bands of β-gal, PSD95 and β-actin (Western blot); J The relative expression of β-gal over WT-9 M; K The relative expression of PSD95 over WT-9 M. Results are expressed as mean ± SD. n = 4. *P < 0.05, **P < 0.01 vs WT-9 M group