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Fig. 7 | Behavioral and Brain Functions

Fig. 7

From: Naringin provides neuroprotection in CCL2-induced cognition impairment by attenuating neuronal apoptosis in the hippocampus

Fig. 7

Effects of Naringin on PAG, GLAST, and GLT-1mRNA expression in the hippocampus of CCL2-treated rats. Quantitative real-time PCR analysis of messenger (m)RNA levels. Relative expression of: a The PAG mRNA. b The GLAST mRNA. c The GLT-1 mRNA. qPCR analysis showed increased expression of PAG mRNA while decreased expression of GLAST, GLT-1 mRNA in hippocampus of CCL2 rats, This result showing that Naringin significantly decreased expression of PAG mRNA while significantly increased GLAST, GLT-1 mRNA in CCL2 group rat.The experiments were repeated four times independently. Values are expressed as mean ± SEM, n = 4 (#P < 0.05, ##P < 0.01 vs sham, *P < 0.05, **P < 0.01 vs CCL2)

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