Association between cerebral dopamine neurotrophic factor (CDNF) 2 polymorphisms and schizophrenia susceptibility and symptoms in the Han Chinese population

Table 1 Genotype and allele frequencies of SNPs in the CDNF2 gene in patients with SZ and controls

dbSNP ID	Stage	Allele (D/d)^a	Patients						Controls						P value^c		Combine P value
			n^b	HWE (p)	Genotype			MAF	n^b	HWE (P)	Genotype			MAF	P value^c		Combine P value
			n^b	HWE (p)	DD	Dd	dd	MAF	n^b	HWE (P)	DD	Dd	dd		Genotype	Allele	Genotype	Allele
rs2577074	1	G/A	528	0.35	144	253	131	0.49	528	0.12	140	281	107	0.469	0.14	0.09	0.43	0.89
rs2577074	2	G/A	142	0.58	44	73	25	0.18	173	0.32	41	93	39	0.225	0.28	0.13	0.43	0.89
rs2577075	1	A/G	527	0.37	143	253	131	0.49	527	0.13	140	280	107	0.469	0.15	0.29	0.15	0.14
rs2577075	2	A/G	142	0.58	44	73	25	0.18	170	0.22	40	93	37	0.218	0.30	0.15	0.15	0.14
rs2249810	1	G/A	528	0.18	186	242	100	0.42	528	0.43	189	261	78	0.395	0.18	0.38	0.04	0.03
rs2249810	2	G/A	139	0.83	63	62	14	0.10	172	0.65	59	81	32	0.186	0.04	0.01	0.04	0.03
rs6506891	1	T/A	526	0.00	285	143	98	0.32	526	0.00	299	151	76	0.288	0.19	0.38	0.78	0.41
rs6506891	2	T/A	142	0.93	64	63	15	0.11	173	0.81	58	83	32	0.185	0.04	0.01	0.78	0.41
rs2118343	1	C/G	528	0.83	309	191	28	0.23	526	0.32	318	187	21	0.218	0.56	0.41	0.76	0.45
rs2118343	2	C/G	142	0.53	97	42	3	0.02	173	0.18	101	58	14	0.081	0.03	0.02	0.76	0.45

Significant values has been emphasized by italic
^aMajor/minor allele, major and minor alleles are denoted by D and d, respectively
^bNumber of samples which are well genotyped
^cP values in the parenthesis were analyzed with 10,000 random permutations

ISSN: 1744-9081