4′-O-β-d-glucosyl-5-O-methylvisamminol, an active ingredient of Saposhnikovia divaricata, attenuates high-mobility group box 1 and subarachnoid hemorrhage-induced vasospasm in a rat model

Table 2 Modified Voetsch neuroscores

Group treatment	Head movement	Motor-sensory function	4-limb movement	Sum
Sham-operated	12 ± 0	12 ± 0	6 ± 0	30 ± 0
SAH	5.2 ± 2.2	4.6 ± 1.8	3.1 ± 0.5	12.9 ± 4.5
SAH+vehicle	6.2 ± 2.6	5.5 ± 2.1	2.7 ± 0.8	14.4 ± 7.5
SAH+4OGOMV
100 μg/kg/day	6.9 ± 1. 6	6.5 ± 2.5	3.7 ± 0.5	17.1 ± 4.6
200 μg/kg/day	8.2 ± 2.4	9.6 ± 1.3	4.0 ± 1.0	21.7 ± 4.7
400 μg/kg/day	9.6 ± 2.5	10.2 ± 3.2*	4.3 ± 1.5	24.1 ± 7.2*

Results are expressed as the mean ± SD, n = 9; *p < 0.01 vs. SAH by Mann–Whitney U test

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