4′-O-β-d-glucosyl-5-O-methylvisamminol, an active ingredient of Saposhnikovia divaricata, attenuates high-mobility group box 1 and subarachnoid hemorrhage-induced vasospasm in a rat model

Table 1 Modified limb-placing test (MLPT)

Group treatment	Ambulation	Placing/stepping reflex	MDI
Sham-operated	0	0	0
SAH	1.28 ± 0.17	1.50 ± 0.13	2.78 ± 0.30
SAH+vehicle	1.28 ± 0.11	1.58 ± 0.21	2.86 ± 0.32
SAH+4OGOMV
100 μg/kg/day	0.91 ± 0. 60	1.54 ± 0.25	2.45 ± 0.85
200 μg/kg/day	0. 82 ± 0.25	0.83 ± 0.43*	1.65 ± 0.68
400 μg/kg/day	0.56 ± 0.22*	0.65 ± 0.20*	1.21 ± 0.42*

Results are expressed as the mean ± SD, n = 9; *p < 0.01 vs. SAH condition by Mann–Whitney U test

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