Figure 3

The expressions of p-ERK1/2 and ERK1/2 in hippocampus, IHC Staining × 400. A: Control group, B: Modeled group, C: Treated group; 1: p-ERK1/2, 2: ERK1/2 (Positive cells were pointed by black arrow). In control group, a large amount of p-ERK1/2 positive cells stained as brownish yellow could be observed. Compared with control group, neurons in model group were stained lightly and the number of p-ERK1/2 positive cells reduced significantly. In treated group, the number of p-ERK1/2 positive cells was more than that in model group. A large amount of ERK1/2 positive cells can be observed in each group with no significant difference.