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Table 3 Demographic and clinical characteristics of AD subjects with delusions only compared to subjects with delusions and hallucinations

From: Genetic association between APOE*4 and neuropsychiatric symptoms in patients with probable Alzheimer's disease is dependent on the psychosis phenotype

 

Delusions without hallucinations (D) (n=445)**

Delusions and hallucinations (D+H) (n=93)**

P value*

Male, frequency (%)

129 (29%)

19 (20%)

.120

APOE ε4 allele frequency

  

.116

0 APOE ε4 alleles

191 (43%)

50 (54%)

 

1 APOE ε4 allele

218 (49%)

39 (42%)

 

2 APOE ε4 alleles

36 (8%)

4 (4%)

 

Age at assessment, mean (SD)

77.4 (5.8)

77.7 (6.9)

.732

Duration of illness (years)

4.1 (2.6)

5.0 (3.2)

.010

Education (years)

12.3 (2.9)

11.8 (2.5)

.091

Baseline MMSE

17.1 (5.6)

15.4 (6.0)

.010

Baseline CDR

1.35 (0.65)

1.75 (0.76)

<.001

  1. *Chi-square test for gender and allele frequency; t-test for all others.
  2. ** 2 subjects missing all hallucination domain data are omitted from this analysis.
  3. Abbreviations: APOE, apolipoprotein E; SD, standard deviation; MMSE, Mini-Mental State Examination; CDR, Clinical Dementia Rating scale.