Concentrations of amino acids in neostriatal extracts. Both male and female control-fed SHRs showed significantly reduced levels of glycine (Gly) when compared to WKY controls, and n-3 PUFA supplementation increased Gly levels significantly in both SHR sexes. In contrast, GABA levels from SHR controls were significantly lower than in WKY controls of both sexes, and n-3 PUFA supplementation did not change the level of GABA. Taurine (Tau) levels were significantly lower in the male SHR controls than in the male WKY controls. n-3 PUFA supplementation promoted a small, non-significant decrease in Tau levels in both sexes. Aspartate (Asp) and serine (Ser) remained unchanged. Data are presented as means ± SEM (n = 4–8), and the level of significance is symbolized with * (p-value ≤ 0.05), ** (p-value ≤ 0.01) or *** (p-value ≤ 0.001). The p-values are calculated by comparison with the mid bar representing control-fed SHRs.