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Table 4 FBAT-PC results for behavioral (factors 1 + 2) and cognitive impulsivity (factors 3 + 4)

From: The influence of serotonin- and other genes on impulsive behavioral aggression and cognitive impulsivity in children with attention-deficit/hyperactivity disorder (ADHD): Findings from a family-based association test (FBAT) analysis

Factors 1 & 2 (behavioral impulsivity)
Gene SNP Allele Frequency Model Under/Over Transmitted Inform. Families p-value Power FDR p-value
Nominal significance
BDNF rs7103411 C 0.20927 2 O 91 0.021263 9 0.10746
BDNF rs10767664 T 0.20889 2 O 87 0.021492 10 0.10746
DRD4 rs3758653 C 0.17287 2 O 52 0.008178 4 0.08178
HTR1E rs1406946 A 0.44805 1 U 338 0.031630 1 0.26692
PNMT rs2934966 T 0.04997 0 O 102 0.027007 2 0.10349
TPH2 rs6582071 A 0.22517 2 U 95 0.010714 10 0.10714
Factors 3 & 4 (cognitive impulsivity)
Gene wide significance
PNMT rs200173 A 0.02383 0 O 40 0.003818 1 0.00936
PNMT rs200173 A 0.02383 1 O 40 0.004680 4 0.00936
Nominal significance
BDNF rs13306221 A 0.05762 1 O 140 0.042211 6 0.22758
DRD1 rs686 G 0.35975 0 U 427 0.006978 6 0.06978
DRD1 rs686 G 0.35975 1 U 336 0.023762 8 0.11881
HTR1E rs1406946 A 0.44805 1 O 338 0.034898 1 0.38387
HTR2A rs6561333 T 0.43307 2 U 288 0.012237 4 0.12237
HTR2A rs1923886 C 0.41760 2 U 278 0.033097 5 0.16548
HTR3B rs1672717 C 0.39106 2 U 234 0.040249 4 0.20125
HTR3B rs3782025 C 0.45063 2 U 266 0.026497 6 0.20125
SLC6A3 rs13189021 T 0.23494 2 U 103 0.018997 9 0.18997
TPH2 rs1352250 A 0.43298 1 O 359 0.011413 2 0.06598
TPH2 rs10879352 T 0.39596 1 O 364 0.015048 4 0.06598
TPH2 rs1487275 G 0.28429 1 O 356 0.019794 9 0.06598
  1. Model: 0 = additive, 1 = dominant, 2 = recessive
  2. Under/Over Transmitted: O = over-transmitted, U = under-transmitted
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