Characteristics | rs9939609 | rs8050136 | rs1421085 | rs9930506 | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AA + AT | TT | T or x2 | P | AA + AC | CC | t or x2 | p | CC + CT | TT | t or x2 | p | GG + AG | AA | t or x2 | p | |
Male/female (n) | 27/23 | 101/86 | 0.000 | 0.999 | 25/21 | 103/88 | 0.003 | 0.959 | 25/23 | 103/86 | 0.090 | 0.764 | 35/34 | 93/75 | 0.423 | 0.516 |
Age (years) | 29.0 ± 7.5 | 26.9 ± 6.8 | −1.819 | 0.07 | 29.1 ± 7.7 | 26.9 ± 6.8 | −1.912 | 0.057 | 27.8 ± 7.5 | 27.3 ± 6.9 | −0.427 | 0.67 | 27.7 ± 7.3 | 27.2 ± 6.9 | −0.487 | 0.627 |
Age of illness onset (years) | 26.2 ± 5.5 | 24.7 ± 4.7 | 1.949 | 0.053 | 26.3 ± 5.6 | 24.7 ± 4.7 | 1.772 | 0.81 | 24.8 ± 5.2 | 25.1 ± 4.9 | −0.393 | 0.695 | 24.9 ± 4.8 | 25.0 ± 5.0 | −0.174 | 0.86 |
Disease duration (months) | 6.6 ± 4.9 | 7.5 ± 4.2 | −1.334 | 0.183 | 6.5 ± 4.2 | 7.6 ± 4.3 | −1.517 | 0.131 | 7.1 ± 3.9 | 7.4 ± 4.4 | −0.427 | 0.670 | 7.5 ± 4.4 | 7.5 ± 4.3 | 0.411 | 0.682 |
Education (years) | 13.3 ± 2.5 | 13.2 ± 3.0 | −0.246 | 0.806 | 13.3 ± 2.6 | 13.2 ± 3.0 | −0.296 | 0.767 | 13.2 ± 3.0 | 13.2 ± 2.9 | −0.104 | 0.917 | 13.6 ± 3.1 | 13.0 ± 2.9 | −1.223 | 0.223 |
Baseline | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Weight (kg) | 63.0 ± 10.8 | 59.5 ± 10.1 | 2.14 | 0.033* | 62.6 ± 10.9 | 59.7 ± 10.2 | 1.707 | 0.089 | 61.7 ± 10.1 | 59.9 ± 10.4 | 1.065 | 0.288 | 58.2 ± 10.1 | 61.1 ± 10.4 | −2.012 | 0.045* |
BMI(kg/m2) | 22.4 ± 3.2 | 21.2 ± 2.8 | 2.383 | 0.020* | 22.3 ± 3.3 | 21.3 ± 2.8 | 1.955 | 0.055 | 22.1 ± 3.0 | 21.3 ± 2.9 | 1.637 | 0.103 | 21.0 ± 3.0 | 21.7 ± 2.9 | −1.7272 | 0.085 |
Six months | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Weight (kg) | 71.7 ± 10.3 | 67.0 ± 9.8 | 2.949 | 0.004* | 71.1 ± 10.4 | 67.2 ± 9.9 | 2.354 | 0.019* | 68.9 ± 9.8 | 67.7 ± 10.1 | 0.714 | 0.476 | 65.8 ± 10.0 | 68.9 ± 9.984 | −2.132 | 0.034* |
BMI (kg/m2) | 25.5 ± 3.0 | 23.9 ± 2.7 | 3.628 | 0.000* | 25.4 ± 3.0 | 24.0 ± 2.7 | 3.009 | 0.003* | 24.7 ± 2.8 | 24.2 ± 2.8 | 1.215 | 0.226 | 23.8 ± 3.0 | 24.5 ± 2.7 | −1.786 | 0.075 |